کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3970291 1256715 2014 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Capacitation and acrosome reaction changes α-tubulin immunodistribution in human spermatozoa
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
پیش نمایش صفحه اول مقاله
Capacitation and acrosome reaction changes α-tubulin immunodistribution in human spermatozoa
چکیده انگلیسی

Tubulin is a protein constituent of cytoskeletal microtubules, closely related to sperm motility. However, the changes in tubulin distribution following capacitation and acrosome reaction are poorly understood. This study immunolocalized and quantified the expression of α-tubulin in fresh, capacitated and acrosome-reacted samples. Immunocytochemical data showed that in capacitated and acrosome-reacted spermatozoa, α-tubulin is labelled throughout most of the flagellum (⩾66.66%). However, the mean α-tubulin-labelled area in these samples was significantly lower than in fresh samples (P < 0.05). Thus, there are different sperm clusters distinguished by their α-tubulin immunoreactivity and this could be directly linked to structural changes following capacitation and acrosome reaction.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Reproductive BioMedicine Online - Volume 28, Issue 2, February 2014, Pages 246–250
نویسندگان
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