کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4077108 1410900 2016 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Maximum load to failure of high dose versus low dose gamma irradiation of anterior cruciate ligament allografts: A meta-analysis
ترجمه فارسی عنوان
حداکثر بار برای شکستن دوز بالا در برابر تابش گاما با دوز کم در تمام الگوریتم های رباط صلیبی قدامی: یک متاآنالیز
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی ارتوپدی، پزشکی ورزشی و توانبخشی
چکیده انگلیسی

BackgroundThe objective of this study was to systematically evaluate the existing literature to compare the biomechanical effects of low dose and high dose gamma irradiation on commonly used ACL allografts.MethodsA systematic search was performed in PubMed, Cumulative Index for Nursing and Allied Health Literature (CINAHL), Cochrane Reviews, SCOPUS, and SportDiscus. Nine studies were identified that met the following inclusion criteria: 1) controlled laboratory study, 2) investigation of standard allografts for anterior cruciate ligament reconstruction (ACLR), 3) gamma irradiation (dose reported) and a negative control group, and 4) mechanical loading (results reported).ResultsNine studies met all inclusion and exclusion criteria. There was a dose-dependent relationship between radiation and decreased mechanical tendon integrity. Low dose radiation (< 2.5 Mrad [Mrad]) showed graft weakening with an average of 4.3% decrease in load to failure (standardized mean difference [SMD], 0.23; 95% CI 0.216, 0.68; p = 0.31), whereas high-dose radiation showed a significantly larger (32.4% average) decrease in load to failure (SMD, 1.79; 95% CI 1.194, 2.38; p < 0.001).ConclusionsGamma irradiation has a negative effect on tendon allograft strength that is dose-dependent, with particularly large effects noted at irradiation doses of ≥ 2.5 Mrad.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Knee - Volume 23, Issue 5, October 2016, Pages 755–762
نویسندگان
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