Mismatch of delayed perfusion volume between TTP and Tmax map of perfusion MRI

ObjectiveTo look for another set of parameters to predict the change in infarct size in acute stroke patients with a perfusion-weighted imaging (PWI)–diffusion-weighted imaging (DWI) mismatch.Materials and MethodsWe reviewed 54 patients who had PWI-DWI mismatch and vascular occlusion on initial MRI and no recanalization of occluded vessel.ResultsTime-to-peak and time-to-max (TTP-Tmax) perfusion mismatch volume was independently significant as a correlate of infarct volume change (P = .004).ConclusionsThe finding of a large TTP-Tmax perfusion delay mismatch volume in patients with acute stroke who have a PWI-DWI mismatch on an initial MRI may predict that the infarct volume will not increase despite persistent vascular occlusion.