Illustrative case: A patient with cerebral proliferative angiopathy

Cerebral proliferative angiopathy (PA) is rare entity and is a clinical entity, which may be regarded as separate from cerebral AVMs in angioarchitecture, natural history, clinical presentation, and, therefore, treatment and which can be discerned from cerebral AVMs by characteristic imaging features, according to the 2008 “Stoke” paper published by Lasjaunias et al. We report a case of cerebral PA, which presented as a diffuse network of densely enhancing vascular spaces with intermingled normal brain parenchyma. The discrepancy between the large size of the nidus and the small shunting volume, the presence of diffuse angiogenesis, and the small calibre of a multitude of feeding arteries and draining veins were the angiographic hallmarks of this case. Cerebral PA should be considered in the differential diagnosis for cerebral AVMs that occur mostly in young female people.