کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4278374 1611499 2015 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Usefulness of a new inflammation-based scoring system for prognostication of patients with hepatocellular carcinoma after hepatectomy
ترجمه فارسی عنوان
مفید بودن یک سیستم امتیازدهی مبتنی بر التهاب جدید برای پیش بینی بیماری های کارسینوم سلول های حاد پس از هپاتکتومی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی عمل جراحی
چکیده انگلیسی

BackgroundWe investigated whether a preoperative scoring system (the “CRP-AFP Score [CAS]”) based on the serum levels of C-reactive protein and alpha-fetoprotein would predict outcome in patients undergoing hepatectomy for hepatocellular carcinoma.MethodsThe CAS was defined as follows: patients with an elevated level of both C-reactive protein (>.3 mg/dL) and alpha-fetoprotein (>20 ng/mL) were assigned a score of 2, and patients showing one or none of these abnormalities were assigned a score of 1 or 0, respectively.ResultsA total of 349 patients were identified. Pathologic findings, in terms of tumor size, histologic grade, vascular invasion, intrahepatic metastasis, and recurrence rate, worsened as the CAS increased. CAS 2 patients had a poorer 5-year overall survival than CAS 0 or 1 patients (32.2% vs 59.7% vs 49.2%, respectively; P < .001).ConclusionsThe CAS is an informative scoring system that can predict outcome in patients with hepatocellular carcinoma after hepatectomy.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The American Journal of Surgery - Volume 209, Issue 1, January 2015, Pages 187–193
نویسندگان
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