کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4311942 1612916 2017 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Physical exercise induces hippocampal neurogenesis and prevents cognitive decline
ترجمه فارسی عنوان
ورزش فیزیکی باعث ایجاد نوروژنز هیپوکامپ و جلوگیری از کاهش شناختی می شود
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
چکیده انگلیسی
Accumulating evidence from animal and human research indicate that adult hippocampal neurogenesis plays a key role in cognition. Meanwhile, cognitive decline is well known to associate with ageing-related neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD). Therefore, prevention of hippocampal neurogenesis reduction should be critical for these diseases. Physical exercise, a potent enhancer of adult hippocampal neurogenesis, has emerged as a potential therapy or an adjunctive therapeutic strategy for cognitive decline. In this review, we discuss the recent findings on hippocampal neurogenesis and the incorporation of new born neurons into the neuronal network in humans and in rodents. By focusing on hippocampal neurogenesis, we illustrate the role and possible mechanisms of physical exercise in cognition preservation.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Behavioural Brain Research - Volume 317, 15 January 2017, Pages 332-339
نویسندگان
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