کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4378846 | 1617558 | 2006 | 12 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Population dynamics of infectious diseases: A discrete time model
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
بوم شناسی، تکامل، رفتار و سامانه شناسی
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چکیده انگلیسی
Mathematical models of infectious diseases can provide important insight into our understanding of epidemiological processes, the course of infection within a host, the transmission dynamics in a host population, and formulation or implementation of infection control programs. We present a framework for modeling the dynamics of infectious diseases in discrete time, based on the theory of matrix population models. The modeling framework presented here can be used to model any infectious disease of humans or wildlife with discrete disease states, irrespective of the number of disease states. The model allows rigorous estimation of important quantities, including the basic reproduction ratio of the disease (R0) and growth rate of the population (λ), and permits quantification of the sensitivity of R0 and λ to model parameters. The model is amenable to rigorous experimental design, and when appropriate data are available, model parameters can be estimated using statistically robust multi-state capture-mark-recapture models. Methods for incorporating the effects of population density, prevalence of the disease, and stochastic forces on model behavior also are presented.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Ecological Modelling - Volume 198, Issues 1â2, 15 September 2006, Pages 183-194
Journal: Ecological Modelling - Volume 198, Issues 1â2, 15 September 2006, Pages 183-194
نویسندگان
Madan K. Oli, Meenakshi Venkataraman, Paul A. Klein, Lori D. Wendland, Mary B. Brown,