کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4512293 1624827 2016 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A study on in vitro enzyme inhibitory properties of Asphodeline anatolica: New sources of natural inhibitors for public health problems
ترجمه فارسی عنوان
مطالعه ای در مورد خواص مهار کنندگی آنزیمی آزمایشگاهی Anatolica Asphodeline: منابع جدید مهارکننده های طبیعی برای مشکلات بهداشت عمومی
کلمات کلیدی
Asphodeline؛ کولین استراز؛ تیروزیناز؛ گلوکوزیداز؛ دارویی؛ ترکیه
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم زراعت و اصلاح نباتات
چکیده انگلیسی


• Enzyme inhibitory activities of A. anatolica were tested in this study.
• All extracts have remarkable enzyme inhibitory potentials.
• Enzyme inhibitory activities varied significantly the plant parts and solvent used.
• Therefore, this study may be useful for pharmaceutical and food areas.

Asphodeline species are traditionally used as food and medicines. The different extracts (acetone, methanol and water) from different parts (stem, root, seed and leaf) of Asphodeline anatolica were screened for inhibitory potentials on cholinesterase, tyrosinase, α-amylase and α-glucosidase. Enzyme inhibitory effects were investigated by using microplate reader. All studied extracts exhibited remarkable inhibitory effects on the tested enzymes. Generally, acetone and methanol extracts have higher potentials than water extracts. Also, the enzyme inhibitory activities of the extracts varied significantly according to the plant parts as well as the solvent used. R-Met (7.42 mgGALAEs/g extract) and St-Ac (10.74 mgGALAEs/g extract) had the highest acetylcholinesterase and butrylcholinesterase inhibitory activity, respectively. R-Met (22.48 mgKAEs/g extract) exhibited the strongest tyrosinase inhibitory effects, while Se-Ac had the most potent activity on both α-amylase (2.53 mmolACAEs/g extract) and α-glucosidase (6.70 mmolACAEs/g extract). The results suggested that the A. anatolica extract may be useful for food and medicinal applications.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Industrial Crops and Products - Volume 83, May 2016, Pages 39–43
نویسندگان
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