کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5503639 1535593 2017 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Microfluidic technologies for yeast replicative lifespan studies
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی سالمندی
پیش نمایش صفحه اول مقاله
Microfluidic technologies for yeast replicative lifespan studies
چکیده انگلیسی
The budding yeast Saccharomyces cerevisiae has been used as a model organism for the study of aging for over 50 years. In this time, the canonical aging experiment-replicative lifespan analysis by manual microdissection-has remained essentially unchanged. Recently, microfluidic technologies have been developed that may be able to substitute for this time- and labor-intensive procedure. These technologies also allow cell physiology to be observed throughout the entire lifetime. Here, we review these devices, novel observations they have made possible, and some of the current system limitations.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Mechanisms of Ageing and Development - Volume 161, Part B, January 2017, Pages 262-269
نویسندگان
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