Short communicationCopy-number variation of housekeeping gene rpl13a in rat strains selected for nervous system excitability

- Quantitative real-time multicolor multiplex PCR.
- Rat strains differing in excitability of the nervous systems.
- Gene copy number differences.

We evaluated copy number variation (CNV) for four genes in rat strains differing in nervous system excitability. rpl13a copy number is significantly reduced in hippocampus and bone marrow in rats with a high excitability threshold and stress. The observed phenomenon may be associated with a role for rpl13a in lipid metabolism.