کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5536539 | 1402294 | 2017 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Evaluation of storing hepatitis B vaccine outside the cold chain in the Solomon Islands: Identifying opportunities and barriers to implementation
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کلمات کلیدی
HepBbacille Calmette-Guerin vaccineVaccine vial monitorHCWsEPIBCGvvm - VVMExpanded Programme on Immunization - برنامه گسترده ای برای ایمن سازیWorld Health Organization - سازمان بهداشت جهانیOcc - عجبLao PDR - لائوس PDRHealth facility - مرکز بهداشتHBV - هپاتیت بHepatitis B vaccine - واکسن هپاتیت Bhepatitis B virus - ویروس هپاتیت بیHealthcare workers - کارمندان خدمات درمانیWHO - که
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Monovalent Hepatitis B vaccine (HepB) is heat stable, making it suitable for storage outside cold chain (OCC) at 37 °C for 1 month. We conducted an OCC project in the Solomon Islands to determine the feasibility of and barriers to national implementation and to evaluate impact on coverage. Healthcare workers at 13 facilities maintained monovalent HepB birth dose (HepB-BD) OCC for up to 28 days over 7 months. Vaccination data were recorded for children born during the project and those born during 7 months before the project. Timely HepB-BD coverage among facility and home births increased from 30% to 68% and from 4% to 24%, respectively. Temperature excursions above 37 °C were rare, but vaccine wastage was high and shortages common. Storing HepB OCC can increase HepB-BD coverage in countries with insufficient cold chain capacity or numerous home births. High vaccine wastage and unreliable vaccine supply must be addressed for successful implementation.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Vaccine - Volume 35, Issue 21, 15 May 2017, Pages 2770-2774
Journal: Vaccine - Volume 35, Issue 21, 15 May 2017, Pages 2770-2774
نویسندگان
Lucy Breakwell, Jenniffer Anga, Ibrahim Dadari, Nahad Sadr-Azodi, Divinal Ogaoga, Minal Patel,