کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5551045 | 1402937 | 2017 | 12 صفحه PDF | دانلود رایگان |
- Ipomoea batatas L. (cultivar Eshu No. 8) is a new species cultivated in Hubei, China.
- Nineteen purple sweet potato anthocyanins were identified from the purple sweet potato cultivar Eshu No. 8.
- The structure of Peak 18 was peonidin 3-coumaryl-p-hydroxybenzoyl sophoroside-5-glucoside and first identified in purple sweet potato.
- Anthocyanin-rich purple sweet potato extract can effectively protect liver against CCl4-induced liver damage.
The hepatoprotective activity of anthocyanin-rich purple sweet potato extract (APSPE) was demonstrated. Sixty mice were randomly divided into six groups: control group [without carbon tetrachloride (CCl4) or APSPE]; model group (with CCl4 only); positive control group (50Â mg/kg body weight silymarin); low-dose group (100Â mg/kg body weight APSPE); medium-dose group (200Â mg/kg body weight APSPE); and high-dose group (400Â mg/kg body weight APSPE). After 10Â days intragastric administration of the respective supplements, the mice in all groups except control were injected intraperitoneally with CCl4 (0.15% in arachis oil, 10Â mL/kg body weight, intravenous). Twelve hours after CCl4 injection, the mice were measured in terms of liver index, levels of aspartate aminotransferase and alanine aminotransferase in serum, as well as glutathione, superoxide dismutase, and malondialdehyde in liver homogenate. Additionally, the livers of mice were stained with hematoxylin and eosin and sectioned for observation. Nineteen purple sweet potato anthocyanins were identified from the purple sweet potato cultivar Eshu No. 8 and analyzed by liquid chromatography- electrospray ionization-tandem mass spectrometry. Peonidin 3-coumaryl-p-hydroxybenzoyl sophoroside-5-glucoside was first identified in purple sweet potato. The results showed that anthocyanins in Eshu No. 8 had good hepatoprotective activity.
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Journal: Journal of Food and Drug Analysis - Volume 25, Issue 3, July 2017, Pages 607-618