کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5562849 1562785 2017 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Early neurological wake-up test in intubated brain-injured patients: A long-term, single-centre experience
ترجمه فارسی عنوان
آزمون اولیه بیداری عصبی در بیماران ترومای مغزی لوله گذاری شده: یک تجربه طولانی مدت، تک مرکزی
کلمات کلیدی
آسیب تروماتیک مغز؛ تست بیداری؛ آسیب سر؛ وقفه آرامبخشی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی مراقبت های ویژه و مراقبتهای ویژه پزشکی
چکیده انگلیسی

BackgroundIn prehospital setting, a severe traumatic brain injury (TBI) requires tracheal intubation, sedation and mechanical ventilation pending the initial imagery. An early neurological wake-up test (ENWT), soon after the initial imaging assessment, allows a rapid neurological reassessment. This strategy authorises an initial clinical examination of reference with which will be compared the later examinations. The main objective of this study was to describe the characteristics of the patients who underwent an ENWT, and to determine its causes of failure.MethodsWe conducted a retrospective, observational, single-centre study including all intubated TBI admitted in the trauma centre. An ENWT was defined as cessation of sedation within 24 h after TBI. Data concerning patient characteristics, CT-scan results, and outcomes were extracted from a prospective register of all intubated TBI admitted in the ICU. Characteristic of ENWT and causes of failure were retrieved from patient files. A multivariate logistic regression model was developed to determine the risk factors of ENWT failure.ResultsDuring 7 years, 242 patients with intubated TBI were included. An ENWT was started in 96 patients, for an overall rate at 40%. The ENWT was stopped in 38 patients (39.5%), mostly due to neurological deterioration in 27 cases (71%) or respiratory distress in 10 cases (26%). Significant predictors of ENWT failure were: the presence of subdural hematoma with a thickness >5 mm on first imagery (OR = 3.2; 95%CI [1.01-10.28]), and an initial GCS score <5 (OR = 7.4; 95%CI [1.92-28.43]). Prevalence of poor outcome at 1 year was lesser in patients with successful ENWT compared to those with failure or absence of ENWT: 4% vs. 48% and 49% (p < 0.0001).ConclusionsThe ENWT is achieved in 40% of patients, with a success rate of 60.5%. In presence of a subdural hematoma with a thickness >5 mm or an initial GCS score <5, an ENWT failure may be expected.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Australian Critical Care - Volume 30, Issue 5, September 2017, Pages 273-278
نویسندگان
, , , , , , , ,