کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5587519 1568819 2017 16 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Review articlePuberty and structural brain development in humans
ترجمه فارسی عنوان
بررسی وضعیت رشد مغز و مغز در انسان
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی علوم غدد
چکیده انگلیسی


- Physical and hormonal markers of puberty have been linked with brain structure.
- Challenges are discussed, including capturing variability in hormone levels.
- More research is needed on individual differences in pubertal onset and progression.

Adolescence is a transitional period of physical and behavioral development between childhood and adulthood. Puberty is a distinct period of sexual maturation that occurs during adolescence. Since the advent of magnetic resonance imaging (MRI), human studies have largely examined neurodevelopment in the context of age. A breadth of animal findings suggest that sex hormones continue to influence the brain beyond the prenatal period, with both organizational and activational effects occurring during puberty. Given the animal evidence, human MRI research has also set out to determine how puberty may influence otherwise known patterns of age-related neurodevelopment. Here we review structural-based MRI studies and show that pubertal maturation is a key variable to consider in elucidating sex- and individual- based differences in patterns of human brain development. We also highlight the continuing challenges faced, as well as future considerations, for this vital avenue of research.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Frontiers in Neuroendocrinology - Volume 44, January 2017, Pages 122-137
نویسندگان
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