کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5593561 | 1571137 | 2017 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Fructo-oligosaccharides reduce energy intake but do not affect adiposity in rats fed a low-fat diet but increase energy intake and reduce fat mass in rats fed a high-fat diet
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کلمات کلیدی
CARTRPL13AAMMNEFAMC4Rpro-opiomelanocortinPOMCAgRPSCFANPYACCCRHFASfatty acid synthase - اسید چرب سنتازNon-esterified fatty acid - اسید چرب غیر استرادیلیShort chain fatty acids - اسیدهای چرب پایه کوتاهtriglyceride - تریگلیسریدLean body mass - توده بدون چربی بدنHigh-protein diet - رژیم غذایی با پروتئین بالاhigh-fat diet - رژیم غذایی با چربی بالاfructo-oligosaccharide - فروکتلوژیاکاردارEnergy intake - مصرف انرژی corticotropin releasing hormone - هورمون آزاد کننده کورتیکوتروپینbody weight - وزن بدنagouti-related peptide - پپتید مرتبط با agoutiadiposity - چاقیMelanocortin-4 receptor - گیرنده ملانوکورتین-4Neuropeptide Y - یوروپروتئین Y
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
فیزیولوژی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
The ingestion of low or high lipid diets enriched with fructo-oligosaccharide (FOS) affects energy homeostasis. Ingesting protein diets also induces a depression of energy intake and decreases body weight. The goal of this study was to investigate the ability of FOS, combined or not with a high level of protein (P), to affect energy intake and body composition when included in diets containing different levels of lipids (L). We performed two studies of similar design over a period of 5Â weeks. During the first experiment (exp1), after a 3-week period of adaptation to a normal protein-low fat diet, the rats received one of the following four diets for 5Â weeks (6 rats per group): (i) normal protein (14% P/E (Energy) low fat (10% L/E) diet, (ii) normal protein, low fat diet supplemented with 10% FOS, (iii) high protein (55%P/E) low fat diet, and (iv) high protein, low fat diet supplemented with 10% FOS. In a second experiment (exp2) after the 3-week period of adaptation to a normal protein-high fat diet, the rats received one of the following 4 diets for 5Â weeks (6 rats per group): (i) normal protein, high fat diet (35% of fat), (ii) normal protein, high fat diet supplemented with 10% FOS, (iii) high protein high fat diet and (iv) high protein high fat diet supplemented with 10% FOS. In low-fat fed rats, FOS did not affect lean body mass (LBM) and fat mass but the protein level reduced fat mass and tended to reduce adiposity. In high-fat fed rats, FOS did not affect LBM but reduced fat mass and adiposity. No additive or antagonistic effects between FOS and the protein level were observed. FOS reduced energy intake in low-fat fed rats, did not affect energy intake in normal-protein high-fat fed rats but surprisingly, and significantly, increased energy intake in high-protein high-fat fed rats. The results thus showed that FOS added to a high-fat diet reduced body fat and body adiposity.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Physiology & Behavior - Volume 182, 1 December 2017, Pages 114-120
Journal: Physiology & Behavior - Volume 182, 1 December 2017, Pages 114-120
نویسندگان
Zouheyr Hadri, Rojo Rasoamanana, Gilles Fromentin, Dalila Azzout-Marniche, Patrick C. Even, Claire Gaudichon, Nicolas Darcel, Abdelkader Dilmi Bouras, Daniel Tomé, Catherine Chaumontet,