کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5626689 1406326 2017 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Being open minded about neuromodulation trials: Finding success in our “failures”
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی روانپزشکی بیولوژیکی
پیش نمایش صفحه اول مقاله
Being open minded about neuromodulation trials: Finding success in our “failures”
چکیده انگلیسی

As part of the efforts of a multi-disciplinary, international working group focused on ethical issues in neuromodulation for neuro-psychiatric disorders, we propose a novel; strategy for study design which iteratively applies new knowledge to on-going and future trials. Under current practice, device studies may be closed or categorized as “failures” before knowledge embedded in them can be fully mined. We propose the use of an iterative process to gain knowledge from subjects who have responded to those who have not. This approach can help maximize outcomes in non-responders and inform the design of future studies. This more agile yet rigorous methodology leverages information at all stages of investigation and promotes both scientific discovery and; stewardship.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Brain Stimulation - Volume 10, Issue 2, March–April 2017, Pages 181-186
نویسندگان
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