کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5627969 1579798 2017 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Pre-stroke glycemic control is associated with early neurologic deterioration in acute atrial fibrillation-related ischemic stroke
ترجمه فارسی عنوان
کنترل گلیکوزم قبل از سکته مغزی با زودرس نورولوژیک اولیه در سکته مغزی ایسکمیک مرتبط با فیبریلاسیون دائمی
کلمات کلیدی
فیبریلاسیون دهلیزی، سکته مغزی زودرس نورولوژیک اولیه،
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی سیستم های درون ریز و اتونومیک
چکیده انگلیسی

BackgroundIt has been suggested that AF-related ischemic stroke (IS) that is accompanied by atherosclerotic burden have poorer outcomes. The aim of this study was to investigate the importance of pre-stroke glycemic control (PSGC) on the early neurologic deterioration (END) of patients with acute AF-related IS.MethodsWe retrospectively recruited 121 patients with AF-related IS who also had Diabetes mellitus (DM). The HbA1C level was measured in all subjects. END was defined as an increase in the National Institute of Health Stroke Scale (NIHSS) score of 4 NIHSS points within 7 days of symptom onset compared to the initial NIHSS score.ResultsIn this study, 20.7% (25 patients) were classified as having a poor PSGC status with a HbA1C level above 8.0%. In the univariate analysis, a poor PSGC status (p < 0.01), smoking (p = 0.01), severe neurologic deficits at admission (p = 0.01), and a larger size of ischemic lesions on DWI (p < 0.01) were associated with the occurrence of END. In the multivariate model, a poor PSGC status (p = 0.02) and larger size of ischemic lesions on MRI (p < 0.01) were independent predictors of END in acute AF-related IS.ConclusionThe HbA1c level upon admission was independently associated with significant prediction of END in acute AF-related IS.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: eNeurologicalSci - Volume 8, September 2017, Pages 17-21
نویسندگان
, , , , , , , , , ,