کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5639006 1584100 2017 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Ten-year study of postoperative complications following dental extractions in patients with inherited bleeding disorders
ترجمه فارسی عنوان
بررسی 10 ساله عوارض بعد از عمل پس از استخراج دندان در بیماران مبتلا به اختلالات خونریزی ارثی
کلمات کلیدی
هموفیلی، بیماری فون ویلبراند، استخراج دندان، جایگزینی فاکتور، دسموپرسین،
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی دندانپزشکی، جراحی دهان و پزشکی
چکیده انگلیسی

Dental extractions challenge the body's haemostatic mechanism. Postoperative bleeding from dental extraction can be prolonged, or even life threatening in patients with inherited bleeding disorders. Pre- and postoperative clotting factor replacements or systemic desmopressin (ddAVP) have been advocated at our institution to prevent bleeding complications in these patients. This study aimed to assess the postoperative bleeding rate in patients with inherited bleeding disorders that underwent dental extractions at our institution between 2003 and 2012. Patients with inherited bleeding disorders such as haemophilia A, haemophilia B, and von Willebrand's disease were included. Retrospective chart review was conducted. The result showed 53 extraction events occurred in 45 patients over the 10-year period. Ten out of 53 extraction events (18.9%) had postoperative bleeding requiring further factor replacement or ddAVP. Postoperative bleeding in one patient with mild haemophilia A was complicated by the development of inhibitors. Type and severity of bleeding disorder, bone removal, and use of a local haemostatic agent did not have any significant effect on postoperative bleeding. Despite the use of perioperative factors and desmopressin, the postoperative bleeding rates remain high for patients with inherited bleeding disorders. More studies are required to assess the safety and effectiveness of using local haemostatic control to achieve haemostasis following extractions.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Oral and Maxillofacial Surgery - Volume 46, Issue 9, September 2017, Pages 1147-1150
نویسندگان
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