کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5644065 1406970 2017 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The utility of adipose-derived stem cells and stromal vascular fraction for oncologic soft tissue reconstruction: Is it safe? A matter for debate
ترجمه فارسی عنوان
استفاده از سلول های بنیادی حاصل از چربی و کریستال عروق استرومال برای بازسازی انکولوژی نرم بافت نرم: آیا آن ایمن است؟ موضوع بحث
کلمات کلیدی
داروهای احیا کننده، درمان با سلول های بنیادی، پیوند چربی، بازسازی بافت نرم،
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی دندانپزشکی، جراحی دهان و پزشکی
چکیده انگلیسی
Autologous free-fat grafting (AFG) has emerged as an attractive proposition for soft-tissue reconstruction of various contour defects because it obviates more complex reconstructive options and reduces operative times and donor-site morbidity. Nonetheless, a common complication of this procedure is the resorption of the engrafted fat. Cell-assisted lipotransfer (CAL) is now a well-regarded technique where adipose-derived stem cell (ASC)-rich stromal vascular fraction is admixed with lipoaspirate, increasing the volumetric outcome of fat grafts in light of its potent angiogenic and adipogenic properties. Criticisms, however, remain regarding this modality especially for the treatment of post-oncologic defects. Laboratory data has attested to its propensity to perpetuate tumor cells as a result of its paracrine effects on the host microenvironment. This review article aims to present the underlying facts behind ASC therapy and provide meaningful discourse as to its utility in post-oncologic soft tissue reconstruction.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Surgeon - Volume 15, Issue 4, August 2017, Pages 186-189
نویسندگان
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