کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5665595 1591175 2017 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Increasing rates of Clostridium difficile infection in Mexican hospitals
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی و میکروب شناسی (عمومی)
پیش نمایش صفحه اول مقاله
Increasing rates of Clostridium difficile infection in Mexican hospitals
چکیده انگلیسی

IntroductionThe epidemiology of Clostridium difficile infection (CDI) has changed in the last two decades. There is a lack of information regarding incidence and severity of CDI, especially in the developing world.MethodsThis was a retrospective and observational study from four hospitals of three Mexican cities. Patients were diagnosed with CDI when presented with loose stools and had at least one of the following tests positive: toxins assay, real-time PCR, or an endoscopic image compatible with pseudomembranous colitis. CDI was classified according to international guidelines. Demographic and clinical data as well as information regarding total hospital admissions, total length-of-hospital stay, and other variables related to hospitalization were gathered from the epidemiology and administration departments of each hospital.ResultsA total of 2050 hospital beds were analyzed with 288,171 patients hospitalized accumulating 1,576,446 days of hospitalization during the study period. The average rate of CDI per 1000 hospital-days was lower than the rates reported in the US and Europe, although in 2015 CDI rates were almost persistently above the mean rate for the study period. More than half of PCR positive patients were ribotype 027.ConclusionHospital rates of CDI are increasing in Mexican hospitals with a predominance of infections caused by ribotype 027.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Brazilian Journal of Infectious Diseases - Volume 21, Issue 5, September–October 2017, Pages 530-534
نویسندگان
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