Protocolo diagnóstico de las anemias hemolíticas

The diagnosis of HA is based on a careful clinical history, with emphasis on family antecedents, physical examination to recognize the hemolytic syndrome, and the typical laboratory findings with regenerative anemia, increased indirect bilirubin and decreased haptoglobin in blood. In the etiologic diagnosis a Coombs test and the morphological study of peripheral blood smear by an expert hematologist are essential. The presence of schistocytes suggests the diagnosis of Microangiopathic HA that requires urgent treatment.