کد مقاله کد نشریه سال انتشار مقاله انگلیسی ترجمه فارسی نسخه تمام متن
5685796 1409034 2017 4 صفحه PDF ندارد دانلود رایگان
عنوان انگلیسی مقاله
Bile Cast Nephropathy Caused by Obstructive Cholestasis
کلمات کلیدی
Cholestasis; acute kidney injury (AKI); renal failure; bile cast nephropathy; cholemic nephrosis; obstructive cholestasis; bile duct obstruction; kidney biopsy;
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری‌های کلیوی
پیش نمایش صفحه اول مقاله
Bile Cast Nephropathy Caused by Obstructive Cholestasis
چکیده انگلیسی

Acute kidney injury (AKI) is a major complication in patients with liver disease. Although hepatorenal syndrome is frequently involved, bile cast nephropathy, characterized by tubular bile cast formation, has been scarcely described in the setting of severe liver failure. Few renal histology studies are available in these patients. We describe a case of bile cast nephropathy in a patient with obstructive cholestasis caused by stones in the common bile duct. The kidney biopsy confirmed this diagnosis, with several green casts in tubular lumens, tubular injury, and bilirubin composition of the tubular casts with Hall stain. The patient had no confounding cause of kidney failure, and complete kidney recovery followed removal of the bile duct obstruction. This case shows that severe cholestasis is sufficient to cause AKI, and that AKI can be reversible after treatment of the biliary obstruction.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: American Journal of Kidney Diseases - Volume 69, Issue 1, January 2017, Pages 143-146
نویسندگان
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