Arguments pour différencier les cancers du sein associés à la grossesse de ceux diagnostiqués dans le post-partum : expérience monocentrique du réseau cancer associé à la grossesse (CALG)

Median gestational age at diagnosis was 16 weeks of gestation (WG). Median size (P = 0.92), initial axillary pathology (P = 0.29), histological type (P = 0.33) and hormone receptor positive (P = 0.93), were similar between groups. PABC during pregnancy overexpressed less frequently HER2 (12 % vs 36 %, P = 0.003) and were less proliferant (Ki67 ≥ 15 %; 64 % vs 75 %, P = 0.018) with less radical surgery (45 % vs 70 %, P = 0.008). Sentinel lymph node biopsy was performed in 8 patients during pregnancy. Less patients of PABC during pregnancy received trastuzumab 12 % vs 37 %, P = 0.003. Median delivery term was 37 WG. Median follow-up 3.2 vs 5.6 years (P = 0.002) and recurrence rate for PABC during pregnancy and of postpartum were 3.2 vs 5.6 years (P = 0.002) and 12 % vs 32 % (P = 0.01), respectively. Our results emphasize histological, surgical and adjuvant treatment differences imposing differentiating PABC during pregnancy from those diagnosed in the postpartum period.