کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5718069 1607092 2017 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
ClinicalPredictive value of procalcitonin for intestinal ischemia and/or necrosis in pediatric patients with adhesive small bowel obstruction (ASBO)
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پریناتولوژی (پزشکی مادر و جنین)، طب اطفال و بهداشت کودک
پیش نمایش صفحه اول مقاله
ClinicalPredictive value of procalcitonin for intestinal ischemia and/or necrosis in pediatric patients with adhesive small bowel obstruction (ASBO)
چکیده انگلیسی

PurposeEvaluate serum procalcitonin (PCT) level as a predictor of intestinal ischemia or necrosis (IN) in patients with postoperative adhesive small bowel obstruction (ASBO).MethodsProspective cohort of consecutive patients with ASBO. Patients previously treated with antibiotics or septic were excluded. PCT was measured at the diagnosis of ASBO and every 24 h afterwards. Main outcome: intestinal ischemia or necrosis (IN).ResultsFifty-nine patients were included, 12 of whom were excluded; 47 patients remained in the study; male-to-female ratio = 1.9:1. Management: medical in 15 cases (32%) and surgical in 32 (68%). Main outcome: Intestinal necrosis (IN) in 10 patients (21.3%). Mean PCT level was higher in patients with IN (15.11 ng/ml vs. 0.183 ng/ml, p = 0.002), the proportion of patients with elevated PCT (> 0.5 ng/dl) was higher in patients with IN (70% vs. 8.1%, p =<0.001, RR = 26.4 with a 95% CI of 4.39-159.5). Elevated PCT levels at diagnosis had a 70% positive predictive value (PPV) and 91.8% negative predictive value (NPV) for prediction of IN. With a PCT value at diagnosis of > 1.0 ng/dl, PPV was 87.5% and NPV, 92.3%.ConclusionsPCT levels are closely related to the presence of intestinal ischemia and necrosis in children with ASBO.Level of evidenceStudy of Diagnostic Test, Level II.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Pediatric Surgery - Volume 52, Issue 10, October 2017, Pages 1616-1620
نویسندگان
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