کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5721697 1608100 2018 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Research paperQuality of life and functioning of Hispanic patients with Major Depressive Disorder before and after treatment
ترجمه فارسی عنوان
کیفیت زندگی و عملکرد بیماران اسپانیایی با اختلال افسردگی عمده قبل و بعد از درمان
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی روانپزشکی و بهداشت روانی
چکیده انگلیسی


- Hispanics and non-Hispanics reported similar depression at entry and exit.
- Hispanic had worse QOL at entry and exit (not after controlling for baseline QOL).
- Significant improvements in QOL, functioning, and depression following treatment.
- Hispanics were less likely to have private insurance compared to non-Hispanics.

BackgroundSimilar rates of remission from Major Depressive Disorder (MDD) have been documented between ethnic groups in response to antidepressant treatment. However, ethnic differences in functional outcomes, including patient-reported quality of life (QOL) and functioning, have not been well-characterized. We compared symptomatic and functional outcomes of antidepressant treatment in Hispanic and non-Hispanic patients with MDD.MethodsWe analyzed 2280 nonpsychotic treatment-seeking adults with MDD who received citalopram monotherapy in Level 1 of the Sequenced Treatment Alternatives to Relieve Depression study. All subjects (239 Hispanic, 2041 non-Hispanic) completed QOL, functioning, and depressive symptom severity measures at entry and exit.ResultsHispanic participants had significantly worse QOL scores at entry and exit (p < 0.01). However, after controlling for baseline QOL, there was no difference between Hispanic and non-Hispanic patients' QOL at exit (p = 0.21). There were no significant between-group differences at entry or at exit for depressive symptom severity or functioning. Both groups had significant improvements in depressive symptom severity, QOL, and functioning from entry to exit (all p values < 0.01). Patients with private insurance had lower depressive symptom severity, greater QOL, and better functioning at exit compared to patients without private insurance.LimitationsThis study was a retrospective data analysis, and the Hispanic group was relatively small compared to the non-Hispanic group.ConclusionsHispanic and non-Hispanic participants with MDD had similar responses to antidepressant treatment as measured by depressive symptom severity scores, quality of life, and functioning. Nevertheless, Hispanic patients reported significantly worse quality of life at entry.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Affective Disorders - Volume 225, 1 January 2018, Pages 117-122
نویسندگان
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