Research paperSpecificity and overlap of attention and memory biases in depression

- Attentional and memory bias do not overlap in explaining depressive symptoms.
- Memory bias is reliably related to depressive symptoms, but not to anxiety symptoms.
- Memory bias is reliably related to mood and cognitive symptoms.
- Attentional bias is not related to depressive symptoms.

BackgroundAttentional and memory biases are viewed as crucial cognitive processes underlying symptoms of depression. However, it is still unclear whether these two biases are uniquely related to depression or whether they show substantial overlap.MethodsWe investigated the degree of specificity and overlap of attentional and memory biases for depressotypic stimuli in relation to depression and anxiety by means of meta-analytic commonality analysis. By including four published studies, we considered a pool of 463 healthy and subclinically depressed individuals, different experimental paradigms, and different psychological measures.ResultsMemory bias is reliably and strongly related to depression and, specifically, to symptoms of negative mood, worthlessness, feelings of failure, and pessimism. Memory bias for negative information was minimally related to anxiety. Moreover, neither attentional bias nor the overlap between attentional and memory biases were significantly related to depression.LimitationsLimitations include cross-sectional nature of the study.ConclusionsOur study showed that, across different paradigms and psychological measures, memory bias (and not attentional bias) represents a primary mechanism in depression.