کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5723114 1608916 2016 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Total or partial vertebrectomy for lung cancer invading the spine
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی سیاست های بهداشت و سلامت عمومی
پیش نمایش صفحه اول مقاله
Total or partial vertebrectomy for lung cancer invading the spine
چکیده انگلیسی


- Surgery for lung cancer invading the spine remains challenging.
- We describe our surgical approach and assess the outcome.
- We experienced eight patients who were treated with partial or total vertebrectomy.
- Five years overall survival rate was 71.4%.

BackgroundSurgery for lung cancer invading the spine remains challenging associated with high morbidity and mortality. However, recent advances in surgical techniques as well as in perioperative care may improve outcomes of lung cancer surgery with vertebrectomy. We describe our surgical approach and assess the outcome lung cancer invading the spine.MethodsWe retrospectively reviewed our recent experiences of lung cancer with vertebral invasion, in which we have performed total or partial vertebrectomy from January 2011 through April 2015.ResultsWe experienced eight patients who were treated with partial or total vertebrectomy for lung cancer. Vertebral invasion was evaluated by chest CT and MRI findings. All cases were no distant metastasis. N factors were all patients N0 revealed by chest CT and PET-CT. Two patients were treated preoperative induction therapy (CDDP + TS-1, Radiation 50 Gy). For the surgery, total vertebrectomy was performed two patients, hemi vertebrectomy was two patients, transverse-process resection was four patients. In all of eight cases, complete resection were perfomed with total or partial vertebrectomy. Morbidity was observed in six patients (75%); no mortality occurred. Six patients (75%) were survived after surgery (range: 12-62 months) and four patients (50%) were no recurrence. Five years overall survival rate was 71.4%.ConclusionsIn our experience, Lung cancer surgery combined with vertebrectomy is highly aggressive surgery associated with high morbidity. But, this procedure is a promising treatment option for selected patients, for example N0M0 disease with lung cancer invading the spine.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Annals of Medicine and Surgery - Volume 12, December 2016, Pages 1-4
نویسندگان
, , , , , , , , , , , , ,