کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5737778 | 1614728 | 2017 | 27 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Motor training and the combination of action observation and peripheral nerve stimulation reciprocally interfere with the plastic changes induced in primary motor cortex excitability
ترجمه فارسی عنوان
آموزش حرکتی و ترکیبی از مشاهدات عمل و تحریک عصبی محیطی با تغییرات پلاستیکی ناشی از تحریک پذیری مغزی اولیه مواجه هستند
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کلمات کلیدی
MEPAPBNIBSTMSMotor training - آموزش موتورPeripheral nerve stimulation - تحریک عصبی محیطیNon-invasive brain stimulation - تحریک مغزی غیر تهاجمیTranscranial magnetic stimulation - تحریک مغناطیسی مغزlong-term potentiation - تقویت درازمدتLTP - تقویت طولانی مدت یا LTP Abductor pollicis brevis muscle - عضله پللیس بروی رحم کنندهprimary motor cortex - قشر حرکتی اولیهAction observation - مشاهده فعالیتmotor-evoked potential - پتانسیل حرکت موتورAssociative plasticity - پلاستیک وابستهPNS - کارمندان دولت
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب (عمومی)
چکیده انگلیسی
AO-PNS is a stimulation protocol combining action observation (AO) and peripheral nerve stimulation (PNS) to induce plasticity in the primary motor cortex (M1) (increased excitability). Another method to increase M1 excitability is motor training. The combination of two protocols, which individually induce long-term potentiation (LTP)-like plasticity in overlapping neural circuits, results in a transitory occlusion or reverse of this phenomenon. This study aimed to understand the neurophysiological mechanisms underlying AO-PNS by testing whether AO-PNS and motor training induced LTP-like plasticity in, at least partially, overlapping neural networks. One group of participants practiced a motor training (finger opposition movements) followed by AO-PNS, whereas another group performed the two protocols in reverse order. Motor performance was evaluated by means of a sensor-engineered glove and transcranial magnetic stimulation was used to assess M1 excitability before and after each conditioning protocol. Motor training increased movement frequency, suggesting the occurrence of motor learning in both groups. When applied on first, both motor training and AO-PNS significantly increased the motor-evoked potential (MEP), but occluded the increase of cortical excitability expected after the following protocol, leading to a significant decrease of MEP amplitude. These results suggest that motor training and AO-PNS act on partially overlapping neuronal networks, which include M1, and that AO-PNS might be able to induce LTP-like plasticity in a similar way to overt movement execution. This candidates AO-PNS as methodology potentially useful when planning rehabilitative interventions on patients who cannot voluntarily move.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience - Volume 348, 21 April 2017, Pages 33-40
Journal: Neuroscience - Volume 348, 21 April 2017, Pages 33-40
نویسندگان
Ambra Bisio, Laura Avanzino, Monica Biggio, Piero Ruggeri, Marco Bove,