کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5795739 1110677 2014 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Seasonal and individual variation in hepatic copper concentrations in a flock of Norwegian Dala sheep
ترجمه فارسی عنوان
تنوع فصلی و فردی در غلظت های کبدی در یک گله گوسفند نروژی دال
کلمات کلیدی
گوسفند، فلز مس، مسمومیت مزمن مس، بیوپسی کبدی،
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم دامی و جانورشناسی
چکیده انگلیسی

This study focused on a flock of Dala sheep with recurrent cases of chronic copper (Cu) poisoning. The seasonal variation in hepatic Cu concentration was followed in individual sheep with repeated liver biopsies, four times per year, in two consecutive years. Thirty-six ewes were included, yielding a total of 279 biopsies. Cu concentrations were measured by atomic absorption spectroscopy. Hepatic Cu concentrations remained almost stable from December to March, fell substantially from March to June, and rose sharply during the summer pasture period from June to October. There were large individual differences in hepatic Cu levels. These differences remained stable through the two years. Treatment with ammonium tetrathiomolybdate (3 × 3.4 mg per kg bodyweight (bw) s.c.) in June had only weak and inconsistent effect on hepatic Cu levels in October. The results may partly explain why chronic Cu poisoning in sheep in Norway predominantly occur in the autumn and winter months.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Small Ruminant Research - Volume 116, Issue 1, January 2014, Pages 57-65
نویسندگان
, ,