کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5797554 | 1555236 | 2016 | 4 صفحه PDF | دانلود رایگان |
- Snakebite envenomation is an important problem for the livestock industry in Costa Rica.
- The clinical manifestations of envenoming by Bothrops asper (family Viperidae) in cattle are described.
- Accidental envenomation following a B.âasper snakebite was reproduced experimentally.
- The administration of equine-derived whole IgG antivenom was effective in treating B.âasper snakebite envenomation.
Snakebite envenoming is an important problem in the livestock industry in Costa Rica. Of the 22 species of venomous snakes in the country, Bothrops asper is involved in most animal envenomings. Envenomation is typically characterised by swelling and bleeding at the bite site, coagulopathy, systemic haemorrhage, and, in some cases, death. The aims of the present study were to describe the clinical manifestations of B.âasper envenomation in cattle and to evaluate the treatment efficacy of antivenom administration.The clinical effects of naturally occurring envenomation were reproduced experimentally in cattle by giving an intramuscular injection of either 10âmg or 50âmg venom to replicate mild and severe envenomings, respectively. Intravenous antivenom given 6âh after experimental venom injection controlled the symptoms; a dose of 120âmL was found to be appropriate for moderate and 200âmL for severe naturally occurring envenomings. Although administration of antivenom within the first 6âh following a snakebite prevented systemic effects, it did not reduce the extent of swelling at the bite site. Delayed administration of antivenom was not effective in saving naturally envenomed animals. The results indicate that, when promptly administered, antivenom constitutes an effective treatment for B.âasper snakebite envenomation in cattle.
Journal: The Veterinary Journal - Volume 207, January 2016, Pages 160-163