کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5800407 1555355 2014 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Experimental nasal colonization of piglets with methicillin-susceptible and methicillin-resistant Staphylococcus aureus
ترجمه فارسی عنوان
کلونیزاسیون نواری تجربی خوک ها با استافیلوکوک اورئوس مقاوم به متسییلین و مقاوم به متسییلین
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم دامی و جانورشناسی
چکیده انگلیسی


- MRSA and MSSA were able to co-colonize in the noses of pigs.
- Nasal colonization and co-colonization remained stable during for 2 weeks.
- This model is suitable for quantitative analysis of colonization of MRSA and MSSA.

Methicillin-resistant Staphylococcus aureus sequence type (ST)398 is widely spread among livestock. People in contact with livestock have a higher risk of testing positive for MRSA. Several experimental settings have been described to study in vivo colonization of MRSA in pigs, each having its own limitations. The aim of this study was to develop a nose-colonization model in pigs to quantitatively study the colonization of MRSA and the co-colonization of MSSA and MRSA.Two experiments were performed: in the first experiment piglets received an intranasal inoculation with MRSA ST398, spa-type t011, and in the second experiment piglets received an intranasal inoculation with two MSSA strains (ST398, spa-type t011 and t034) and two MRSA strains (also ST398, spa-type t011 and t034) to investigate co-colonization. Colonization was quantitatively monitored for 2 weeks in both experiments.Nasal colonization was successfully established in all piglets with stable numbers of S. aureus between 104 and 106 CFU. MSSA and MRSA were able to co-colonize.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Veterinary Microbiology - Volume 174, Issues 3–4, 5 December 2014, Pages 483-488
نویسندگان
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