Bacterial lysates as a potentially effective approach in preventing acute exacerbation of COPD

► The use of bacterial lysates to reduce AECOPDs is an intriguing concept. ► They are powerful inducers of a specific immune response against bacteria. ► Their mechanism of action is still not fully understood. ► Bacterial lysates lower bacterial carriage levels in the respiratory tract. ► They are a potentially effective approach in preventing AECOPDs.