Lack of association between translin-associated factor X gene (TSNAX) and methamphetamine dependence in the Japanese population

► The TSNAX might be a good candidate gene for methamphetamine dependence. ► 215 patients with methamphetamine dependence and 318 age- and sex-matched controls. ► Three 'tagging SNPs' in TSNAX were selected. ► TSNAX was not associated with methamphetamine dependence in the Japanese population. ► A replication study using larger samples needs in the future.