کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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5885831 | 1150928 | 2013 | 6 صفحه PDF | دانلود رایگان |
PurposeOur aims were to determine whether the pulse oximetric saturation/fraction of inspired oxygen (S/F) can be used for the early identification of patients with sepsis who are at increased risk for death and to compare the S/F ratio with the Pao2/fraction of inspired oxygen (P/F) ratio.Materials and MethodsThis is a retrospective cohort study in 260 patients admitted to 2 tertiary mixed intensive care units (ICUs) with severe sepsis or septic shock. We studied the association between tertiles of S/F ratio and ICU mortality using Cox regression. Subsequently, we compared corresponding measurements of S/F ratio and P/F ratio upon ICU admission using Pearson correlation coefficient (r).ResultsWe observed an overall case fatality of 72 (28%) of 260. After adjustment for severity of the illness, the lowest tertile (S/F, <Â 164) at ICU admission was associated with increased mortality (hazard ratio, 1.87 [95% confidence interval, 1.02-3.41]) comparing to the highest tertile (S/F, >Â 236). The S/F ratio was correlated with P/F ratio (r = 0.48; P < .0001).ConclusionA low S/F at ICU admission is associated with increased risk of death in patients with severe sepsis or septic shock.
Journal: Journal of Critical Care - Volume 28, Issue 5, October 2013, Pages 681-686