کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5901614 | 1156126 | 2011 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Identification and gene expression analysis of three GnRH genes in female Atlantic cod during puberty provides insight into GnRH variant gene loss in fish
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موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
علوم غدد
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چکیده انگلیسی
⺠We have identified three pre-pro-gonadotropin releasing hormone (GnRH) genes in female Atlantic cod (Gadus morhua). ⺠One variant, gmGnRH1, appears to be a pseudogene based on sequence and phylogenetic analysis. ⺠The putative gmGnRH1 pseudogene is expressed in multiple tissues but at low levels in the brain. ⺠gmGnRH2 and gmGnRH3 are highly expressed in female brains and to a lesser extent in the pituitary and ovaries. ⺠gmGnRH3 is upregulated during spawning, suggesting that a functional shift has led to gmGnRH3 acting as the hypophysiotrophic form in Atlantic cod.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: General and Comparative Endocrinology - Volume 172, Issue 3, 1 July 2011, Pages 458-467
Journal: General and Comparative Endocrinology - Volume 172, Issue 3, 1 July 2011, Pages 458-467
نویسندگان
Jon Hildahl, Guro K. Sandvik, Rolf B. Edvardsen, Cathrine Fagernes, Birgitta Norberg, Trude M. Haug, Finn-Arne Weltzien,