کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5908835 | 1570170 | 2015 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Does host receptivity or host exposure drives dynamics of infectious diseases? The case of West Nile Virus in wild birds
ترجمه فارسی عنوان
آیا پذیرش میزبان یا میزبان در معرض دینامیک بیماری های عفونی است؟ مورد ویروس غرب نیل در پرندگان وحشی
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کلمات کلیدی
پاتوژن چند میزبان، روند عفونت، غرب نیل، پذیرش، عوامل محیطی،
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
بوم شناسی، تکامل، رفتار و سامانه شناسی
چکیده انگلیسی
Infection is a complex biological process involving reciprocally both the intensity of host exposure to a pathogen as well as the host intrinsic “receptivity”, or permissiveness to infection. Disentangling their respective contributions is currently seen as a fundamental gap in our knowledge. Here, we take the advantage of a rare semi-natural experiment context provided by the emergence of the West Nile Virus (WNV) in North America. Focusing on the pathogen emergence period, we combine datasets from (i) wild birds exposed to WNV in an urban zoo to evaluate the species intrinsic receptivity to WNV infection in an environment where exposure to WNV vectors can be assumed to be relatively homogenous for all captive species, and (ii) from free-ranging birds in their natural habitat where species ecological traits is expected to influence their exposure to WNV vectors. We show that ecological trait and intrinsic receptivity to infection both contribute similarly to the species variation in WNV seroprevalence, but considering only one of them can lead to erroneous conclusions. We then argue that degree of pathogen host specialization could be a fundamental factor for the respective contribution of species exposure and receptivity for numerous pathogens.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Infection, Genetics and Evolution - Volume 33, July 2015, Pages 11-19
Journal: Infection, Genetics and Evolution - Volume 33, July 2015, Pages 11-19
نویسندگان
Benjamin Roche, Serge Morand, Eric Elguero, Thomas Balenghien, Jean-François Guégan, Nicolas Gaidet,