کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5908922 | 1570170 | 2015 | 6 صفحه PDF | دانلود رایگان |
- First report of a G8P[14] RVA strain detected in Guatemala, Latin America.
- First report of RVA strain with G8-P[14]-I2-R2-C2-M2-A13-N2-T6-E2-H3 constellation.
- This G8P[14] RVA strain occupies lineage VII within the P[14] genotype.
We report the genomic characterization of a rare human G8P[14] rotavirus strain, identified in a stool sample from Guatemala (GTM) during routine rotavirus surveillance. This strain was designated as RVA/Human-wt/GTM/2009726790/2009/G8P[14], with a genomic constellation of G8-P[14]-I2-R2-C2-M2-A13-N2-T6-E2-H3. The VP4 gene occupied lineage VII within the P[14] genotype. Phylogenetic analysis of each genome segment revealed close relatedness to several zoonotic simian, guanaco and bovine strains. Our findings suggest that strain RVA/Human-wt/GTM/2009726790/2009/G8P[14] is an example of a direct zoonotic transmission event. The results of this study reinforce the potential role of interspecies transmission and reassortment in generating novel and rare rotavirus strains which infect humans.
Journal: Infection, Genetics and Evolution - Volume 33, July 2015, Pages 206-211