Oral gabapentin suppresses pentylenetetrazole-induced seizure-like behavior and cephalic field potential in adult zebrafish

► Oral gabapentin pretreatment suppressed PTZ-induced seizures in adult zebrafish. ► The anticonvulsant effects were significant and dose-dependent. ► Novel oral delivery method in adult zebrafish ascertaining accurate dose in mg/kg ► 1st report to study both behavior and cephalic field potential in one study ► This provides a novel framework for evaluating modulators of epilepsy in zebrafish.