Specificity of psychopathology in temporal lobe epilepsy

► Mean anxiety and depression scores were higher than those of the standardization sample. ► On MMPI-2 scales that resembled the IDD and TLE Personality Syndrome: ► Application of MMPI-2 to the investigation of psychopathology in TLE suggests lack of specificity. ► Groups of patients with TLE were not clinically elevated compared with matched controls. ► Patterns of the IDD and TLE Personality Syndrome could not be supported.