کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6051645 1583324 2013 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
ReviewAn evolutionary perspective of mammal salivary peptide families: Cystatins, histatins, statherin and PRPs
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی دندانپزشکی، جراحی دهان و پزشکی
پیش نمایش صفحه اول مقاله
ReviewAn evolutionary perspective of mammal salivary peptide families: Cystatins, histatins, statherin and PRPs
چکیده انگلیسی

Saliva's role in the oral cavity, such as lubrication, protection of tissues and antimicrobial action is a reflex of its composition, among which are several peptide families like statherin, histatins, proline rich proteins (PRPs) and some members of the cystatin family. These peptides present different evolutionary pathways being in the case of histatin, statherin and PRP families restricted to few millions and comprising few species when compared with cystatins, where duplication occurred at more than 650 mya. Though the recognized relevance of phylogenetic approaches to disclose relationships among different species, information on the salivary proteins that allow the association between peptide families-related structure and function in the oral cavity is scarce. In the present study, the four major salivary peptides classes are reviewed considering the few known phylogenetic studies focusing on their evolution among mammals. New perspectives and challenges for future and multidisciplinary experimental works are drawn.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Archives of Oral Biology - Volume 58, Issue 5, May 2013, Pages 451-458
نویسندگان
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