کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6055343 | 1198798 | 2011 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Bisphosphonate related osteonecrosis of the jaw - Manifestation in a microvascular iliac bone flap
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
دندانپزشکی، جراحی دهان و پزشکی
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![عکس صفحه اول مقاله: Bisphosphonate related osteonecrosis of the jaw - Manifestation in a microvascular iliac bone flap Bisphosphonate related osteonecrosis of the jaw - Manifestation in a microvascular iliac bone flap](/preview/png/6055343.png)
چکیده انگلیسی
Bisphosphonate related osteonecrosis of the jaw (BRONJ) is a side effect that may emerge due to a long-term bisphosphonate therapy. Although the timely diagnosis and initiation of treatment are associated with good outcome results, extended cases require whole parts of the jaw to be resected. A possible treatment option is the bony reconstruction of the jaw using microvascular bone flaps. We report, for the first time, the development of a bisphosphonate related osteonecrosis in a microvascular iliac bone graft, a reconstruction that was performed following a partial mandibulectomy due to BRONJ stage III. The observation of BRONJ manifestation in an osseous microvascular transplant is a novel finding that sheds new light on current pathogenesis theories that surround this entity. Furthermore, it is hypothesized that BRONJ is able to progress to adjacent bone. In addition, bone reconstruction in patients suffering from BRONJ may be seen more critically.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Oral Oncology - Volume 47, Issue 5, May 2011, Pages 425-429
Journal: Oral Oncology - Volume 47, Issue 5, May 2011, Pages 425-429
نویسندگان
Christoph Pautke, Sven Otto, Simone Reu, Andreas Kolk, Michael Ehrenfeld, Stephen Stürzenbaum, Klaus-Dietrich Wolff,