کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6063141 | 1201848 | 2015 | 11 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Olfaction in allergic rhinitis: AÂ systematic review
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کلمات کلیدی
VASRCTHyposmiaUPSIT - UPSIRandomized controlled trial - آزمایش تصادفی کنترل شدهOdor threshold - آستانه بویاییAllergy - آلِرژیAnosmia - آنزیمیاsmell - بوolfaction - بویاییOdor discrimination - تبعیض بویاییUniversity of Pennsylvania Smell Identification Test - دانشگاه پنسیلوانیا تست شناسایی بوی بد دهانRhinitis - رینیتAllergic rhinitis - رینیت آلرژیکOdor identification - شناسایی بویMedical Subject Heading - عنوان موضوع پزشکیMesh - مشvisual analog scale - مقیاس آنالوگ بصری
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Olfactory dysfunction is a key symptom in patients with allergic rhinitis (AR). Despite the implications for quality of life, relatively few articles have tested olfactory function in their investigations. The current systematic review aimed to investigate the following 2 questions: (1) What does AR do to human olfaction? (2) How effective is the treatment of AR in restoring the sense of smell? AÂ comprehensive literature search was performed, and human studies of any design were included. AÂ total of 420 articles were identified, and 36 articles were considered relevant. Data indicate that the frequency of olfactory dysfunction increases with the duration of the disorder, and most studies report a frequency in the range of 20% to 40%. Although olfactory dysfunction does not appear to be very severe in patients with AR, its presence seems to increase with the severity of the disease. There is very limited evidence that antihistamines improve olfactory function. In addition, there is limited evidence that topical steroids improve the sense of smell, especially in patients with seasonal AR. This is also the case for specific immunotherapy. However, many questions remain unanswered because randomized controlled trials are infrequent and only a few studies rely on quantitative measurement of olfactory function.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Allergy and Clinical Immunology - Volume 136, Issue 6, December 2015, Pages 1460-1470
Journal: Journal of Allergy and Clinical Immunology - Volume 136, Issue 6, December 2015, Pages 1460-1470
نویسندگان
Boris A. MD, Thomas MD,