کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6099715 | 1211051 | 2013 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A case of opportunistic skin infection with Mycobacterium marinum during adalimumab treatment in a patient with Crohn's disease
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کلمات کلیدی
IBDTSTAdalimumabIGRATuberculin skin test - آزمایش پوست توبرکولینCrohn's disease - بیماری کرونInflammatory bowel disease - بیماریهای التهابی رودهInterferon-gamma release assay - تست آزمایشگاهی Interferon-gammaAnti-TNF - ضد TNFAnti-TNF Therapy - ضد TNF درمانMycobacterium marinum - مایکوباکتریوم مارینومC-reactive protein - پروتئین واکنشی سیCRP - پروتئین واکنشی سی یا سی. آر. پی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
بیماریهای گوارشی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Opportunistic infections, especially reactivation with M. tuberculosis, are major complications during treatment with anti-TNF agents. Infections with atypical mycobacteria like Mycobacterium marinum are rare and tend to turn into a difficult and prolonged course due to delayed diagnosis. This is the first case of M. marinum infection during adalimumab therapy in a patient with Crohn's disease. The most important diagnostic step was a detailed medical history as PCR tested for M. tuberculosis and for atypical subspecies was false negative. Up to now a discontinuation of anti-TNF therapy has been recommended, however, there is no consensus about the reintroduction of biologicals after sufficient anti-infective therapy. In this patient anti-TNF therapy had to be reintroduced because of increasing activity with no relapse of M. marinum after a follow-up of 12Â months.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Crohn's and Colitis - Volume 7, Issue 1, February 2013, Pages e15-e18
Journal: Journal of Crohn's and Colitis - Volume 7, Issue 1, February 2013, Pages e15-e18
نویسندگان
Patrizia K. Kump, Christoph Högenauer, Heimo H. Wenzl, Wolfgang Petritsch,