Odorant-evoked electrical responses in Grueneberg ganglion neurons rely on cGMP-associated signaling proteins

► Neurons in the Grueneberg ganglion generate electrical signals upon stimulation with the odorant 2,3-dimethylpyrazine. ► These responses rely on the guanylyl cyclase GC-G and the cyclic nucleotide-gated channel CNGA3. ► cGMP signaling is important for odorant-evoked electrical responses in the Grueneberg ganglion.