کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6286383 | 1298068 | 2013 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Dual compartments of the ventral division of the medial geniculate body projecting to the core region of the auditory cortex in C57BL/6 mice
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب (عمومی)
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چکیده انگلیسی
We investigated precise projection patterns from the ventral division of the medial geniculate body (MGv) projecting to the core region of the auditory cortex in C57BL/6 mice. The core region in mice comprises two different tonotopically organized areas, the anterior auditory field (AAF) and the primary auditory cortex (AI). In the present study, AAF and AI were functionally identified using flavoprotein fluorescence imaging. Biotinylated dextran amine (BDA) was injected iontophoretically into the tonotopic bands to 5Â kHz and 20Â kHz in AAF, and those to 5Â kHz, 10Â kHz, and 20Â kHz in AI for staining MGv neurons projecting to the injected sites. MGv neurons projecting to AAF were found in the medial part of MGv, while MGv neurons projecting to AI were found in the lateral part. In the medial part of MGv, areas projecting to 5-20Â kHz bands in AAF were aligned along the medio lateral axis. In the lateral part of MGv, areas projecting to 5-20Â kHz bands in AI were aligned along the dorso ventral axis. These results indicate that AAF and AI receive auditory information via two different MGv compartments with independent tonotopic axes, respectively.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience Research - Volume 76, Issue 4, August 2013, Pages 207-212
Journal: Neuroscience Research - Volume 76, Issue 4, August 2013, Pages 207-212
نویسندگان
Masao Horie, Hiroaki Tsukano, Ryuichi Hishida, Hirohide Takebayashi, Katsuei Shibuki,