Iron metabolism and its relationship to anemia and immune system in Trypanosoma evansi infected rats

► T. evansi infection can cause erythrophagocytosis. ► Accumulate iron in the bone marrow of infected animals. ► Reduction of serum levels of iron and prohepcidin. ► Increase in serum levels of transferrin and ferritin. ► Changes in iron metabolism related to the immune response and anemic status of rats infected.