کد مقاله کد نشریه سال انتشار مقاله انگلیسی ترجمه فارسی نسخه تمام متن
6312659 1308757 2016 7 صفحه PDF سفارش دهید دانلود کنید
عنوان انگلیسی مقاله
Full length articleTraffic-related air pollution increased the risk of Parkinson's disease in Taiwan: A nationwide study
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم محیط زیست شیمی زیست محیطی
پیش نمایش صفحه اول مقاله
Full length articleTraffic-related air pollution increased the risk of Parkinson's disease in Taiwan: A nationwide study
چکیده انگلیسی


- Traffic-related pollutants NOx and CO increase the risk of PD.
- High levels of coarse particles contribute to the increased risk of PD.
- Traffic-related air pollution may adversely affect the aging brain.

BackgroundAmbient air pollution has been associated with many health conditions, but little is known about its effects on neurodegenerative diseases, such as Parkinson's disease (PD). In this study, we investigated the influence of ambient air pollution on PD in a nationwide population-based case-control study in Taiwan.MethodsWe identified 11,117 incident PD patients between 2007 and 2009 from the Taiwanese National Health Insurance Research Database and selected 44,468 age- and gender-matched population controls from the longitudinal health insurance database. The average ambient pollutant exposure concentrations from 1998 through the onset of PD were estimated using quantile-based Bayesian Maximum Entropy models. Basing from logistic regression models, we estimated the odds ratios (ORs) and 95% confidence intervals (CIs) of ambient pollutant exposures and PD risk.ResultsWe observed positive associations between NOx, CO exposures, and PD. In multi-pollutant models, for NOx and CO above the 75th percentile exposure compared with the lowest percentile, the ORs of PD were 1.37 (95% CI = 1.23-1.52) and 1.17 (95% CI = 1.07-1.27), respectively.ConclusionsThis study suggests that ambient air pollution exposure, especially from traffic-related pollutants such as NOx and CO, increases PD risk in the Taiwanese population.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Environment International - Volume 96, November 2016, Pages 75-81
نویسندگان
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