کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6351552 | 1622555 | 2016 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Hydroxylated polybrominated diphenyl ethers (OH-PBDEs) in paired maternal and neonatal samples from South China: Placental transfer and potential risks
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم محیط زیست
بهداشت، سم شناسی و جهش زایی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Hydroxylated polybrominated diphenyl ethers (OH-PBDEs) in paired maternal and neonatal samples from South China: Placental transfer and potential risks Hydroxylated polybrominated diphenyl ethers (OH-PBDEs) in paired maternal and neonatal samples from South China: Placental transfer and potential risks](/preview/png/6351552.png)
چکیده انگلیسی
Hydroxylated polybrominated diphenyl ethers (OH-PBDEs) are attracting more and more attention for the neurodevelopment toxicity effects. We evaluated the concentrations of 15 individual OH-PBDEs and 3 bromophenol (BRP) congeners in 30 mother-newborn paired placenta, breast milk, fetal cord blood, and neonatal urine samples collected from South China. The geometric mean (GM) concentrations of âOH-PBDEs were 37.6, 61.3, and 76.8 pg gâ1 ww in placenta, breast milk, and cord blood, respectively. The GM concentrations of âBRPs were 47.6, 119, and 30.2 pg gâ1 ww in placenta, breast milk, and cord blood, respectively. The GM concentrations of âOH-PBDEs and âBRPs in neonatal urine were 72.0 and 79.8 pg mlâ1, respectively. Of the 15 OH-PBDE congeners analyzed, the three most frequently detected congeners were 2â²-OH-BDE-68 (72.1%), 6-OH-BDE-47 (67.6%), and 2â²-OH-BDE-28 (65.8%). The estimated daily intake (EDI) of OH-PBDEs for the breast-fed infants was 9.31±4.00 ng kgâ1 bw day. The accumulation of OH-PBDEs in newborns was much lower than the estimated lowest observed-effect concentration (LOEC) of neurotoxicity. The present study provided the first systematic fundamental data that exposure to OH-PBDEs for newborn and their mothers in South China.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Environmental Research - Volume 148, July 2016, Pages 72-78
Journal: Environmental Research - Volume 148, July 2016, Pages 72-78
نویسندگان
Zhuo-Jia Chen, Han-Yan Liu, Ka-Lok Ho, Hong-Bin Huang, Qing Liu, Yu-Bon Man, Michael Hon-Wah Lam, Jun Du, Ming-Hung Wong, Hong-Sheng Wang,