کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6369343 | 1623820 | 2016 | 8 صفحه PDF | دانلود رایگان |
- The role of underdominance in population connectivity is discussed.
- A simple model incorporating migration and underdominance in a meta-population with varying network topologies is presented.
- Simulations of underdominance with migration suggest the network topology of a meta-population is important to long term genetic stability.
Heterozygote disadvantage is potentially a potent driver of population genetic divergence. Also referred to as underdominance, this phenomena describes a situation where a genetic heterozygote has a lower overall fitness than either homozygote. Attention so far has mostly been given to underdominance within a single population and the maintenance of genetic differences between two populations exchanging migrants. Here we explore the dynamics of an underdominant system in a network of multiple discrete, yet interconnected, populations. Stability of genetic differences in response to increases in migration in various topological networks is assessed. The network topology can have a dominant and occasionally non-intuitive influence on the genetic stability of the system.
Journal: Journal of Theoretical Biology - Volume 390, 7 February 2016, Pages 156-163