Activation of AKT signaling promotes cell growth and survival in α7β1 integrin-mediated alleviation of muscular dystrophy

►Signaling is altered in a mouse model of Duchenne muscular dystrophy (mdx/utr−/−). ►AKT signaling may provide the mechanistic basis for α7 integrin-mediated therapy. ►ILK associates with α7B integrin at a critical tyrosine residue upon activation.